Bacterial Lifestyle Alters the Evolution of Drug Resistance

Bacterial Lifestyle Alters the Evolution of Drug Resistance 10/23/2019 PITTSBURGH – How bacteria live — whether as independent cells or in a communal biofilm — determines how they evolve antibiotic resistance, which could lead to more personalized approaches to antimicrobial therapy and infection control.  University of Pittsburgh School of Medicine researchers repeatedly exposed bacteria to the antibiotic ciprofloxacin to force rapid evolution. As expected, the bacteria developed resistance to the drug, but surprisingly, their lifestyle affected which specific adaptations emerged, according to a…

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Protogenes featured in Science and Nature articles

Dr. Anne-Ruxandra Carvunis was recently featured in Nature and Science magazine articles which highlighted her work on de novo gene birth. While one talks about how evolution builds new genes from scratch, the other focuses on the presence of tiny proteins which surprisingly have important phenotypic effects. These articles bring into light the role of Dr. Cavunis’s proposed proto-genes in the two phenomena. Click the images below to view the full articles.

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New Course: Evolutionary Biology in Health and Disease (Spring 2020)

Evolution is a fundamental unifying principle of biology. This class takes a broad approach to illustrate how an evolutionary perspective augments medical research and practice. Topics covered range from the evolution of human populations, to antibiotic resistance, and include medical conditions as diverse as diabetes, cardiovascular disease, cancer or aging. Course Director: Anne-Ruxandra Carvunis. Lecturers: Vaughn Cooper, Erik Wright, Dennis Kostka, and Matt Nicotra Link to the course description:

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Microbiology & Molecular Genetics Seminar Series: Caitlin Pepperell, MD, FRCP (C)

Microbiology & Molecular Genetics Fall 2018 Seminar Series University of Pittsburgh, School of Medicine Caitlin Pepperell, MD, FRCP (C) Associate Professor, Department of Medicine (Infectious Diseases), University of Wisconsin-Madison “Mycobacteria on the move” Host: Dr. Vaughn Cooper *Light refreshments will be served Wednesday, December 12, 2018 Bridgeside Point II, Room 503 12:00 PM – 1:00 PM   Download the flyer here

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2nd Annual Three Rivers Evolution Event (TREE)

We are excited to announce the second annual Three Rivers Evolution Event (TREE), a regional conference serving Western Pennsylvania and the surrounding areas, sponsored in part by SMBE. TREE aims to bring together researchers to share and discuss all aspects of evolutionary biology in a diverse, exciting, and accessible environment. Last year, 168 attendees from 38 different institutions joined us in our shared passion for evolution, and we expect our community to grow even larger in 2018. This year’s keynote…

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For inquiries, please contact Kristie Bowman
 Phone: (412) 648-4058

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